Endocrine Abstracts

Gastrointestinal stromal tumour (GIST) is now defined as a specific, KIT-expressing and KIT-signalling driven mesenchymal tumour of the gastrointestinal (GI) tract. We report a case of stromal tumour revealed by prolonged fever and skin lesions associated with primary hyperparathyroidism and pituitary adenoma.Observation: We present the case of a 59-year-old patient admitted for prolonged fever with inflammatory syndrome and latte tasks cutaneous lesions...

TSH-secreting pituitary tumors (TSH-omas) are a rare cause of hyperthyroidism and account for < 1% of all pituitary adenomas. They are usually benign adenomas arising from a monoclonal expansion of neoplastic thyrotropes.We report two patients’ cases with thyrotropinoma.The first case is a 73-year-old woman, who presents a TSH-secreting pituitary adenoma in the setting of multiple endocrine neoplasia syndrome type 1 (TSH-o...

Introduction: Type 2 diabetes is a springboard to metabolic and cardiovascular complications. The objective of our work was to investigate the different cardiovascular risk factors in diabetic type 2 population, and study relation between the level of cardiovascular risk and the occurrence of degenerative complications.Patients and Methods: Retrospective study including 149 patients with type 2 diabetes consultant at the Department of Endocrinology at th...

Introduction: The coexistence of Grave disease [GD] and Myasthenia gravis [MG] may present a diagnostic dilemma especially concerning ocular manifestations. 3–10% of myasthenic patients exhibit GD, while MG is reported in only <1% of patients with thyroid disorder.Observation:Case 1: A 32-year-old woman, with a medical history of vitiligo, was diagnosed with GD. Immunology revealed positive anti-thyroid peroxidase antibod...

Introduction: Incidentally discovered adrenal incidentalomas has been reported to be as high as 5% of abdominal cross-sectional imaging performed for reasons unrelated to the adrenal gland. Although the management of bilateral and unilateral incidentalomas is the same, some studies suggest differences between the two groups.Patients and Methods: Retrospective study including 91 patients with adrenal incidentaloma at the Department of Endocrinology, Charl...

Introduction: Several familial disorders could be associated with adrenal pheochromocytoma such as Von Hippel–Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN2) and, less commonly, neurofibromatosis type 1 (NF1). Herein, we report three cases of pheochromocytoma as a part of genetic syndromes.ObservationsPatient 1A 34-year-old women with no familial history, was diagnosed with severe hype...

Introduction: In 1974, the first case of concomitant thyroid and parathyroid disease was reported. Non-medullary thyroid carcinoma has been reported in 6% of patients with Primary hyperparathyroidism. However, the simultaneous occurrence of parathyroid carcinoma along with non-medullary thyroid carcinoma is extremely rare.Case report: We report a case of 60-year-old woman with a history of Diabetes Mellitus type 2 and hypertension. She had no family hist...

Introduction: Gougerot disease is an autoimmune disorder characterized by the lymphoid infiltration of salivary and lachrymal glands leading to the two most common symptoms dry eyes and a dry mouth. Primary hyperparathyroidism (PHPT), one of the most common endocrine disorders, is usually diagnosed by the association of hypercalcemia and parathyroid hormone (PTH) levels that are either elevated or inappropriately normal. The association of PHPT with Gougerot disease is rare, o...

Introduction: Clinical presentation of hypothyroidism is frequently insidious. Of the many non specific clinical signs of hypothyroidism, ascites is one of the less common manifestations reported and the diagnosis is often made late with this condition. Herein, we present the cases of isolated ascites revealing hypothyroidism in order to drow attention to hypothyroidism as an etiology of an unexplained isolated ascites.Observation: A 61-year-old diabetic...

Introduction: Thyroid ectopy is uncommon pathology. The lingual area is the most frequent localization. The medaistinal localization is rare. We report in this article two cases illustrating this location.1st clinical case66-year-old woman operated on for benign breast cysts consulted for progressive chest pain. The clinical examination was without abnormalities. The standard biological assessment was normal. Cervicothoracic CT sca...